isolated congenital anonychia https://www.malacards.org/card/isolated_congenital_anonychia Isolated congenital anonychia is characterized by nail abnormalities ranging from onychodystrophy (dystrophic nails) to anonychia (absence of nails). Onychodystrophy-anonychia has been described in at least four generations of a family with male-to-male transmission, suggesting autosomal dominant transmission. Anonychia has been described in approximately less than 20 cases; it is likely to be transmitted as an autosomal recessive trait. Total anonychia congenita, in which all the fingernails and toenails are absent, may have an autosomal dominant inheritance pattern. autosomal recessive nonsyndromic congenital nail disorder-4 MEDGEN:120563 nonsyndromic congenital nail disorder, 4 MONDO:0019211 Orphanet:79143 GARD:0010048 isolated anonychia congenital anonychia UMLS:C0265998 inherited isolated nail anomaly