diffuse palmoplantar keratoderma diffuse palmoplantar keratoderma - acrocyanosis syndrome https://www.malacards.org/card/diffuse_palmoplantar_keratoderma_acrocyanosis_syndrome_2 Diffuse palmoplantar keratoderma-acrocyanosis syndrome is characterized by the association of diffuse palmoplantar keratoderma and acrocyanosis. It has been described in eight members of one family and in two sporadic cases. The mode of inheritance in the familial cases was autosomal dominant. Orphanet:86918 diffuse palmoplantar hyperkeratosis-acrocyanosis syndrome MEDGEN:929257 MONDO:0019489 GARD:0019089 UMLS:C4303588