eye disorder developmental anomaly of metabolic origin peroxisome biogenesis disorder Zellweger spectrum disorders https://github.com/monarch-initiative/mondo/issues/2632 https://github.com/monarch-initiative/mondo/issues/7693 https://github.com/monarch-initiative/mondo/pull/2571/ https://www.malacards.org/card/zellweger_syndrome MESH:D015211 The most severe variant seen in the peroxisome biogenesis disorders that is characterized by neuronal migration defects in the brain, dysmorphic craniofacial features, profound hypotonia, neonatal seizures, and liver dysfunction. NANDO:1200760 MEDGEN:21958 DOID:905 GARD:0007917 ZS Zellweger spectrum disorders ZWS Curator note: this refers to the severe form of Zellweger spectrum, see https://github.com/monarch-initiative/mondo-build/issues/61 Zellweger leukodystrophy MONDO:0019609 Zellweger syndrome Orphanet:772 ICD10CM:E71.510 NORD:1876 Orphanet:912 cerebrohepatorenal syndrome SCTID:88469006 UMLS:C0043459 NCIT:C85239 obsolete nephropathy secondary to a storage or other metabolic disease