hereditary disease vascular disorder Marfan and Marfan-related disorder familial thoracic aortic aneurysm and aortic dissection https://github.com/monarch-initiative/mondo/issues/9518 https://www.malacards.org/card/familial_thoracic_aortic_aneurysm_and_aortic_dissection MONDO:0019625 A rare genetic vascular disease characterized by the familial occurrence of thoracic aortic aneurysm, dissection or dilatation affecting one or more aortic segments (aortic root, ascending aorta, arch or descending aorta) in the absence of any other associated disease. Depending on the size, location and progression rate of dilatation/dissection, patients may be asymptomatic or may present dyspnea, cough, jaw, neck, chest or back pain, head, neck or upper limb edema, difficulty swallowing, voice hoarseness, pale skin, faint pulse and/or numbness/tingling in limbs. Patients have increased risk of presenting life threatening aortic rupture. FTAAD Orphanet:91387 nonsyndromic heritable thoracic aortic disease GARD:0002249 nonsyndromic HTAD nsHTAD familial aortic dissection Erdheim disease familial thoracic aortic aneurysm and aortic dissection MEDGEN:1644766 ICD9:447.9 ns-FTAAD OMIMPS:607086 familial non-syndromic TAAD SCTID:45894003 SCTID:764965000 familial TAAD nonsyndromic familial thoracic aortic aneurysm and dissection UMLS:C4707243