eye disorder obsolete syndrome or malformation associated with head and neck malformations isolated ankyloblepharon filiforme adnatum https://github.com/monarch-initiative/mondo/issues/6744 https://www.malacards.org/card/isolated_ankyloblepharon_filiforme_adnatum MONDO:0019626 UMLS:C1302999 MEDGEN:227001 GARD:0019168 icd11.foundation:1002292151 Isolated ankyloblepharon filiforme adnatum (AFA) is characterized by the presence of single or multiple thin bands of connective tissue between the upper and lower eyelids, preventing full opening of the eye. Several cases have been reported. It can occur sporadically or following an autosomal dominant transmission pattern. In some cases, AFA can be associated with other disorders, such as trisomy 18. The bands should be removed to avoid amblyopia and this can easily be performed in the neonatal period by cutting with tissue scissors. Orphanet:91397