iridogoniodysgenesis Rieger anomaly MEDGEN:78558 GARD:0016482 Orphanet:91483 Rieger's anomaly is a congenital ocular defect caused by anterior segment dysgenesis and is characterized by severe anterior chamber deformity with prominent strands and marked atrophy of the iris stroma, with hole or pseudo-hole formation and corectopia. The term covers the association of these iris and pupil anomalies with the features of AxenfeldBs anomaly. MedDRA:10059198 MONDO:0019628 UMLS:C0265341