syndromic disease non-acquired pituitary hormone deficiency pituitary stalk interruption syndrome https://rarediseases.info.nih.gov/diseases/13209/pituitary-stalk-interruption-syndrome https://www.malacards.org/card/pituitary_stalk_interruption_syndrome NCIT:C121150 ectopic neurohypophysis Orphanet:95496 MONDO:0019828 UMLS:C4053775 hypoplastic anterior pituitary, missing stalk, and ectopic posterior pituitary SCTID:715727009 MEDGEN:883774 PSIS icd11.foundation:1474283222 Pituitary stalk interruption syndrome (PSIS) is a congenital abnormality of the pituitary that is responsible for pituitary deficiency and is usually characterized by the triad of a very thin or interrupted pituitary stalk, an ectopic (or absent) posterior pituitary (EPP) and hypoplasia or aplasia of the anterior pituitary visible on MRI. In some patients the abnormality may be limited to EPP (also called ectopic neurohypophysis) or to an interrupted pituitary stalk. GARD:0013209