has characteristic has characteristic congenital heart malformation Laubry-Pezzi syndrome https://github.com/monarch-initiative/mondo/issues/6740 https://www.malacards.org/card/laubry_pezzi_syndrome Laubry-Pezzi syndrome is a rare, non-syndromic, congenital heart malformation characterized by the prolapse of an aortic valve cusp into a subjacent ventricular septal defect due to Venturi effect, resulting in aortic regurgitation. Patients typically present with symptoms of progressive aortic valve insufficiency, such as shortness of breath, heart palpitations, chest pain and exercise intolerance. GARD:0019646 SCTID:764955006 VSD with aortic insufficiency UMLS:C4707235 ventricular septal defect with aortic insufficiency MONDO:0020427 Orphanet:99094 MEDGEN:1643612 has an isolated presentation