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    <!-- http://purl.obolibrary.org/obo/MONDO_0018310 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0018310">
        <rdfs:label>Langerhans cell histiocytosis</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/MONDO_0020519 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0020519">
        <rdfs:label>hand-Schuller-Christian disease</rdfs:label>
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        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/6754</ns3:IAO_0000233>
        <oboInOwl:hasDbXref>ICD9:277.89</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICDO:9753/1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:39795003</oboInOwl:hasDbXref>
        <rdfs:comment>This term&#39;s classification was reviewed in the context of the Strategic Refinement project (2023) and was determined to be excluded from the &#39;https://github.com/monarch-initiative/mondo/issues/6754&#39; (MONDO:0005087) ontology branch (https://orcid.org/0000-0001-9310-0163)</rdfs:comment>
        <ns3:IAO_0000115>A multifocal, unisystem form of Langerhans-cell histiocytosis. There is involvement of multiple sites in one organ system, most frequently the bone. Patients are usually young children presenting with multiple destructive bone lesions.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>multifocal eosinophilic granuloma</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hand-Schuller-Christian disease</oboInOwl:hasExactSynonym>
        <oboInOwl:id>MONDO:0020519</oboInOwl:id>
        <oboInOwl:hasDbXref>GARD:0006567</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C5574737</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>classic multifocal Langerhans cell histiocytosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MEDGEN:1804593</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Orphanet:99873</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>multifocal Unisystem Langerhans cell histiocytosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NCIT:C6920</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chronic multifocal Langerhans cell histiocytosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>hand-SChüller-Christian disease</oboInOwl:hasExactSynonym>
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