disease has basis in disruption of disease caused by disruption of long-chain fatty acyl-CoA dehydrogenase activity disorder of fatty acid oxidation and ketogenesis inborn errors of metabolism long chain acyl-CoA dehydrogenase deficiency GARD:0009700 Orphanet:99900 acyl-CoA dehydrogenase, long-chain deficiency SCTID:237996001 MEDGEN:65087 inborn error of long-chain-acyl-CoA dehydrogenase activity long-chain acyl-Coenzyme A dehydrogenase deficiency long-chain acyl-CoA dehydrogenase deficiency MONDO:0020531 LCAD deficiency ACADL deficiency UMLS:C0220711 long chain acyl-CoA dehydrogenase deficiency rare inborn error of long-chain-acyl-CoA dehydrogenase activity inborn long-chain-acyl-CoA dehydrogenase activity disorder LCAD MESH:C535690 NCIT:C84537 icd11.foundation:692829041 A genetic disorder characterized by deficiency of the enzyme long-chain acyl-coenzyme A dehydrogenase that metabolizes long-chain fatty acids. Signs and symptoms appear in infancy or childhood and may be triggered during fasting, illness or exercise. They include hypoglycemia, muscle weakness and lethargy. familial hypertrophic cardiomyopathy