<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MONDO?iri=http://purl.obolibrary.org/obo/MONDO_0020547"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns5="http://purl.obolibrary.org/obo/mondo#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#otar"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#curated_content_resource"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#exactMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#rare"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#ordo_subtype_of_a_disorder"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#closeMatch"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000053 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000053">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#InverseFunctionalProperty"/>
        <rdfs:label>has characteristic</rdfs:label>
        <rdfs:label xml:lang="en">has characteristic</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/MONDO_0013730 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0013730">
        <rdfs:label>graft versus host disease</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0020547 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0020547">
        <rdfs:label>chronic graft versus host disease</rdfs:label>
        <equivalentClass>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/MONDO_0013730"/>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001863"/>
                    </Restriction>
                </intersectionOf>
            </Class>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0013730"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000053"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0001863"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:seeAlso rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://rarediseases.info.nih.gov/diseases/10964/chronic-graft-versus-host-disease</rdfs:seeAlso>
        <ns5:curated_content_resource rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://www.malacards.org/card/chronic_graft_versus_host_disease</ns5:curated_content_resource>
        <oboInOwl:hasDbXref>MEDGEN:167851</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9:279.52</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCIT:C4981</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SCTID:402356004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GARD:0010964</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:D89.811</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>GVHD, chronic</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>NANDO:2100213</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NANDO:2200812</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0867389</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>chronic GVHD</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>icd11.foundation:621183043</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Orphanet:99921</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MedDRA:10066261</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>graft versus host disease, chronic</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>Chronic graft versus host disease (GVHD) is a complication that can occur after a stem cell or bone marrow transplant in which the newly transplanted donor cells attack the transplant recipient&#39;s body. Symptoms may include skin rash, mouth sores, dry eyes, liver inflammation, development of scar tissue in the skin and joints, and damage to the lungs. The exact cause of chronic GVHD is unknown.It likely results from a complex immune-mediated interaction between the donor and recipient cells.Chronic GVHD is treated with prednisone or other similar anti-inflammatory or immunosuppressive medications.</ns4:IAO_0000115>
        <oboInOwl:id>MONDO:0020547</oboInOwl:id>
        <skos:exactMatch rdf:resource="http://id.who.int/icd/entity/621183043"/>
        <skos:closeMatch rdf:resource="http://identifiers.org/meddra/10066261"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/medgen/167851"/>
        <skos:exactMatch rdf:resource="http://identifiers.org/snomedct/402356004"/>
        <skos:exactMatch rdf:resource="http://linkedlifedata.com/resource/umls/id/C0867389"/>
        <skos:exactMatch rdf:resource="http://purl.bioontology.org/ontology/ICD10CM/D89.811"/>
        <skos:exactMatch rdf:resource="http://purl.obolibrary.org/obo/NCIT_C4981"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#gard_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#nord_rare"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#ordo_subtype_of_a_disorder"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#otar"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/mondo#rare"/>
        <skos:exactMatch rdf:resource="http://www.orpha.net/ORDO/Orphanet_99921"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0001863 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0001863">
        <rdfs:label>chronic</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



