disease has basis in disruption of disease caused by disruption of NMDA glutamate receptor activity paraneoplastic limbic encephalitis steroid-responsive encephalopathy associated with autoimmune thyroiditis encephalitis anti-NMDA receptor encephalitis https://github.com/monarch-initiative/mondo/issues/5765 https://www.malacards.org/card/nmda_receptor_encephalitis MESH:D060426 limbic encephalitis with N-methyl-D-aspartate receptor antibodies MEDGEN:458943 limbic encephalitis with NMDA receptor antibodies MONDO:0021081 NCIT:C94853 anti-NMDA receptor encephalitis UMLS:C2986717 SCTID:716684004 An autoimmune acute encephalitis caused by antibodies against the glutamate NMDA receptor. It usually affects females and in the majority of cases it is associated with the presence of a tumor, most commonly an ovarian teratoma. The presence of a tumor in patients with this form of encephalitis implies that the latter is a paraneoplastic syndrome. It is manifested with psychiatric symptoms and epileptic seizures. It is a potentially lethal disorder; however, it is usually reversible with the prompt removal of the tumor. NANDO:2201317 icd11.foundation:1568915618 Orphanet:217253 GARD:0020513 antibody mediated epilepsy