syndromic disease dermis disorder atrophoderma of Pierini and Pasini https://rarediseases.info.nih.gov/diseases/5866/atrophoderma-of-pierini-and-pasini https://www.malacards.org/card/atrophoderma_of_pierini_and_pasini congenital atrophoderma of Pasini and Pierini Atrophoderma of Pierini and Pasini is thought to possibly represent a late stage of morphea a type of localized scleroderma. Signs and symptoms ofatrophoderma of Pierini and Pasini include multiple oval, darkened (hyperpigmented) plaques in which tissue under the skin breaks downso that there is a depression (dent) within the skin. Some findings suggest that atrophoderma of Pierini and Pasini may be associated with B burgdorferi, a bacteria that causesLyme disease, in some cases. MONDO:0022513 Orphanet:658810 UMLS:C3887897 ICD10CM:L90.3 MEDGEN:854615 idiopathic atrophoderma of Pasini and Pierini GARD:0005866 SCTID:711524008