acute myocarditis giant cell myocarditis https://github.com/monarch-initiative/mondo/issues/7170 https://rarediseases.info.nih.gov/diseases/6502/giant-cell-myocarditis GCM SCTID:60812006 giant cell myocarditis An often fatal inflammatory disorder that affects the myocardium. Morphologically, it is characterized by the presence of an inflammatory infiltrate in the myocardial tissue that includes multinucleated giant cells. It is often associated with the presence of an autoimmune disorder. Patients present with arrhythmias and/or heart failure. Heart transplantation is the only treatment option available. MONDO:0023232 GARD:0006502 icd11.foundation:507103735 idiopathic giant-cell myocarditis NORD:1183 Giant cell myocarditis cases can be idiopathic or occur in various conditions, such as infection (tuberculosis, syphilis, pneumocystis jirovecii parvovirus, coxsackie), inflammation, drug sensitivity, hypersensitivity and vasculitis. At least one group of the condition is considered as an autoimmune disease in 19% of patients in some registries that co-manifest with other autoimmune diseases such as inflammatory bowel disease, cryofibrinogenemia, optic neuritis, Hashimoto thyroiditis, rheumatoid arthritis, Takayasu arteritis, temporal arteritis, myasthenia gravis (MG), alopecia totalis, vitiligo, orbital myositis, autoimmune hepatitis, Guillain-Barré syndrome, systemic lupus erythematosus, Sjögren’s and pernicious anemia. (PMID:33458585) NCIT:C97055