disease has inflammation site otitis media infectious disease ear infection infectious otitis media otitis media infectious otitis Media Inflammation of the anatomical structures of the middle ear secondary to an infectious process. Bacterial etiology is most common, but both viral and fungal pathogens are also possible. Symptoms include erythema and edema of the tympanic membrane, pain, and possibly fever. In severe infections, inflammation and edema of the structures of the middle ear can lead to perforation of the tympanic membrane secondary to the buildup of pressure in the narrow space. MONDO:0024330 middle Ear infection MEDGEN:443472 AOM acute otitis Media NCIT:C84354 UMLS:C2827407 middle ear