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    <!-- http://purl.obolibrary.org/obo/MONDO_0004731 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0004731">
        <rdfs:label>central sleep apnea syndrome</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MONDO_0024360 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MONDO_0024360">
        <rdfs:label>central sleep apnea caused by high altitude</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MONDO_0004731"/>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/monarch-initiative/mondo/issues/8957</ns3:IAO_0000233>
        <oboInOwl:hasExactSynonym>central sleep apnea due to high-altitude periodic breathing</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MEDGEN:884045</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>central sleep apnea due to high altitude</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>SCTID:91441000119109</oboInOwl:hasDbXref>
        <oboInOwl:id>MONDO:0024360</oboInOwl:id>
        <oboInOwl:hasDbXref>UMLS:C4075997</oboInOwl:hasDbXref>
        <rdfs:comment>This term is also called &quot;central sleep apnea due to high-altitude periodic breathing&quot;. However, this term is not the same concept as &quot;central sleep apnea due to periodic breathing&quot; MONDO:0024359 (PMID:27920092; PMID:31604817)</rdfs:comment>
        <ns3:IAO_0000115>A central sleep apnea syndrome induced by sleeping at an altitude higher than 2000 m. Central sleep apnea is caused by improper signaling from the brainstem to the respiratory muscles and is triggered by either hypoventilation or hyperventilation. Clinical signs include snoring, insomnia or hypersomnia, difficulty concentrating, and fatigue. Recurrent episodes of hypoxia/hypoxemia have long-term detrimental effects on cardiovascular health.</ns3:IAO_0000115>
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