disease arises from feature disease has basis in feature malignant superior sulcus neoplasm neoplastic syndrome Pancoast syndrome Pancoast tumor tumor, Pancoast Pancoast tumour MESH:D010178 syndrome, Pancoast MEDGEN:10553 NCIT:C55815 Pancoast syndrome UMLS:C0030271 Pancoast's syndrome A rare neoplastic syndrome characterized by obstruction of the thoracic outlet leading to compression of the brachial plexus and vessels within. It is usually caused by a malignant neoplasm in the superior pulmonary sulcus. The most commonly involved neoplasms are non-small cell lung carcinomas. Clinical signs include Horner's syndrome, shoulder pain radiating down the arm in the ulnar distribution followed by edema and atrophy of the affected extremity. Clinical course usually leads to early local invasion of the bony thoracic structures. Prognosis is highly stage-dependent. Pancoasts syndrome SCTID:278065000 superior pulmonary sulcus syndrome syndrome, Pancoast's MONDO:0024674 GARD:0025455 secondary neoplasm