Aicardi-Goutieres syndrome Aicardi-Goutieres syndrome 9 https://github.com/monarch-initiative/mondo/issues/5261 https://github.com/monarch-initiative/mondo/issues/7365 https://www.malacards.org/card/aicardi_goutieres_syndrome_9 UMLS:C5561966 Aicardi-Goutieres syndrome 9 A type I interferonopathy characterized by severe developmental delay and progressive neurologic deterioration. Patients present in infancy with irritability and spasticity. Brain imaging shows diffusely abnormal white matter, cerebral atrophy, and intracranial calcification. Premature death has been associated with renal and/or hepatic failure. OMIM:619487 GARD:0025553 MONDO:0030362 MEDGEN:1794176 AGS9 RNU7-1-related type 1 interferonopathy