familial hypoaldosteronism late-onset familial hypoaldosteronism https://www.malacards.org/card/late_onset_familial_hypoaldosteronism MONDO:0035321 UMLS:C5680172 Mild aldosterone synthase deficiency Orphanet:556037 ICD10CM:E27.4 A rare form of familial hypoaldosteronism characterized by adult onset of subnormal plasma aldosterone with elevated plasma renin activity, hyperkalemia, metabolic acidosis, and hypotension. Signs and symptoms are typically mild, and affected individuals may be clinically asymptomatic and diagnosed only after biochemical screening. Late-onset familial hyperreninemic hypoaldosteronism MEDGEN:1843290 GARD:0022244