disease arises from structure disease arises from alteration in structure nervous system disorder ectodermal dysplasia syndrome neurocutaneous syndrome Phakomatoses MONDO:0042983 MESH:D020752 syndrome, neuroectodermal dysplasia syndromes, neurocutaneous UMLS:C0265316 syndromes, neuroectodermal dysplasia Phacomatoses Phacomatosis neuroectodermal dysplasia syndrome neurocutaneous disorder syndrome, neurocutaneous neurocutaneous syndrome neurocutaneous disorders phakomatosis NANDO:2100220 NCIT:C84348 A group of disorders characterized by ectodermal-based malformations and neoplastic growths in the skin, nervous system, and other organs. MEDGEN:82706 SCTID:78572006 neuroectodermal dysplasia syndromes A number of genetic and acquired diseases come in this category and may affect one or more of these tissues. However, in some conditions, such as von Hippel-Lindau disease, ectodermal presentation is minimal. Editor note: Phakomatoses are inconsistently defined, and there is a lack of consensus about what conditions are included in this category ectoderm