predisposes towards craniosynostosis inherited disease susceptibility craniosynostosis 7 https://github.com/monarch-initiative/mondo/issues/4521 https://github.com/monarch-initiative/mondo/issues/4882 https://github.com/monarch-initiative/mondo/issues/9815 https://www.malacards.org/card/craniosynostosis_7 MEDGEN:1392447 MONDO:0044315 craniosynostosis 7, susceptibility to DOID:0060912 UMLS:C4479496 Craniosynostosis is a primary abnormality of skull growth involving premature fusion of the cranial sutures such that the growth velocity of the skull often cannot match that of the developing brain. This produces skull deformity and, in some cases, raises intracranial pressure, which must be treated promptly to avoid permanent neurodevelopmental disability (summary by {1:Fitzpatrick, 2013}).nnFor a discussion of genetic heterogeneity of craniosynostosis, see CRS1 (OMIM:123100). Crs7, digenic craniosynostosis 7, digenic CRS7 OMIM:617439 craniosynostosis 7 SMAD6-related disease