disease has location colorectal adenocarcinoma signet ring cell carcinoma colorectal signet ring cell carcinoma MONDO:0044336 MEDGEN:313040 NCIT:C43586 UMLS:C1707440 colorectal signet Ring cell carcinoma An invasive colorectal adenocarcinoma characterized by the presence of malignant glandular epithelial cells with prominent intracytoplasmic mucin resulting in the displacement of the nuclei. The malignant glandular cells with intracytoplasmic mucin constitute more than 50% of the malignant cellular infiltrate. large intestine