toxic dermatosis erythema multiforme major https://www.malacards.org/card/erythema_multiforme_major erythema exsudativum multiforme majus erythema multiforme majus NCIT:C3385 MONDO:0044719 UMLS:C3241919 A severe, sometimes life-threatening, form of erythema multiforme. It is considered to be a hypersensitivity skin reaction triggered by a variety of stimuli, including infections and medication. It is characterized by raised, edematous papules in the extremities; involvement of one or more mucous membranes; and epidermal detachment involving less than ten percent of the total body surface area. GARD:0022049 MEDGEN:469028 Orphanet:502499