blood coagulation disease prekallikrein deficiency SCTID:48976006 prekallikrein deficiency MEDGEN:75779 UMLS:C0272339 GARD:0025905 A condition characterized by the congenital or acquired deficiency of prekallikrein. This deficiency is usually not associated with bleeding. The congenital deficiency is very rare. Acquired deficiency may occur in diffuse intravascular coagulation, infections, and sickle cell disease. NCIT:C99022 NANDO:2200684 MONDO:0044744