has material basis in germline mutation in disease has feature BCAT2 Hypervalinemia Hyperleucinemia inborn disorder of branched-chain amino acid metabolism hypervalinemia and hyperleucine-isoleucinemia 2018-08-31T20:51:10Z https://github.com/monarch-initiative/mondo/issues/4521 https://www.malacards.org/card/hypervalinemia_and_hyperleucine_isoleucinemia branched-chain aminotransferase deficiency MEDGEN:1719306 HVLI MONDO:0100058 hypervalinemia and hyperleucine-isoleucinemia OMIM:618850 UMLS:C5394277 GARD:0026028 hypervalinemia or hyperleucine-isoleucinemia DOID:0060950 Elevated levels of plasma valine and leucine/isoleucine levels, associated with symptoms of headache and mild memory loss and attributed to biallelic variants in the BCAT2 gene. BCAT2 encodes branched-chain aminotransferase 2 which catalyzes the transamination of the branched chain amino acids to their respective α-keto acids.