tyrosine hydroxylase deficiency TH-deficient infantile parkinsonism and motor delay 2018-11-10T00:07:39Z tyrosine hydroxylase infantile parkinsonism and motor delay A tyrosine hydroxylase deficiency with onset typically between age three and 12 months. Motor milestones are overtly delayed in this severe form. Affected infants demonstrate truncal hypotonia and parkinsonian symptoms and signs (hypokinesia, rigidity of extremities, and/or tremor). GARD:0026033 MONDO:0100065