has material basis in germline mutation in IKBKG immunodeficiency disease IKBKG-related immunodeficiency with or without ectodermal dysplasia https://github.com/monarch-initiative/mondo/issues/5520 MONDO:0100162 Any recessive immunodeficiency (ID), with or without ectodermal dysplasia (EDA), in which the cause of the disease is mutation in the IKBKG gene. ID/EDA-ID patients, always males, are hemizygous for an IKBKG (NEMO) mutation that preserves residual NF-κB activation (hypomorphic mutations) and may also present with osteopetrosis and lymphoedema (OL-EDA-ID). NEMO related ID/EDA-ID