has material basis in germline mutation in KRT10 annular epidermolytic ichthyosis ichthyosis, annular epidermolytic 1 https://www.malacards.org/card/ichthyosis_annular_epidermolytic_1 OMIM:607602 GARD:0015417 MONDO:0100303 Any annular epidermolytic ichthiosis in which the cause of the disease is a variation in the KRT10 gene. epidermolytic hyperkeratosis 2