disease has basis in disruption of disease caused by disruption of FNIP1 immunodeficiency disease FNIP1-associated syndrome https://github.com/monarch-initiative/mondo/issues/4021 FNIP1 deficiency immunodeficiency with cardiomyopathy and pre-excitation syndrome MONDO:0100432 Any immunodeficiency in which the cause of the disease is a mutation in the FNIP1 gene. Disruption of Folliculin Interacting Protein 1 alters the essential metabolic regulators AMPK and mTOR, resulting in profound B-cell deficiency, hypertrophic cardiomyopathy, and pre-excitation syndrome. absent B cells, agammaglobulinemia, and hypertrophic cardiomyopathy syndrome