hereditary angioedema hereditary angioedema with normal C1Inh https://github.com/monarch-initiative/mondo/issues/7581 https://www.malacards.org/card/hereditary_angioedema_with_normal_c1inh HAE with normal C1 inhibitor MEDGEN:743231 hereditary angioneurotic edema with normal C1Inh hereditary angioneurotic edema with normal C1 inhibitor GARD:0022195 HAE with normal C1Inh hereditary angioedema with normal C1 inhibitor Orphanet:528647 A rare hereditary angioedema characterized by potentially life-threatening episodes of subcutaneous and/or submucosal edema without urticaria and with normal levels and function of C1 esterase inhibitor. Patients present with prolonged attacks which last for approximately two to five days and may include nonpitting edema of the skin, severe abdominal symptoms such as pain and swelling, and/or respiratory distress due to upper respiratory airways involvement. Affected locations and frequency of attacks differ slightly between subtypes. Estrogen-containing oral contraceptives and pregnancy are precipitating factors, especially in patients with a factor XII mutation. UMLS:C1960459 MONDO:0100567