metabolic disease skeletal fluorosis https://github.com/monarch-initiative/mondo/issues/9097 fluorosis of the skeleton A condition that results from excessive fluoride ingestion leading to fluoride accumulation in the bone progressively over many years. The early symptoms of skeletal fluorosis, include stiffness and pain in the joints. In severe cases, the bone structure may change and ligaments may calcify, with resulting impairment of muscles and pain. ICD10CM:M85.1 icd11.foundation:1269698463 MONDO:0400003