has material basis in germline mutation in ATM hereditary neoplastic syndrome ATM-related cancer predisposition https://github.com/monarch-initiative/mondo/issues/6515 Hereditary cancer predisposition due to variation(s) in the ATM gene. Pathogenic germline variation in ATM confers an autosomal dominant predisposition to tumor formation at multiple primary sites, including breast cancer, ovarian cancer, pancreatic cancer, and prostate cancer. MONDO:0700270 GARD:0026410