hypoalphalipoproteinemia apolipoprotein A-I deficiency https://github.com/monarch-initiative/mondo/issues/7693 Orphanet:425 A lipoprotein metabolism disorder characterized biochemically by complete absence of apolipoprotein AI and extremely low plasma high density lipoprotein (HDL) cholesterol, and clinically by corneal opacities and xanthomas complicated with premature coronary heart disease (CHD). GARD:0028051 MONDO:0700513 MEDGEN:137983 UMLS:C0342898