has material basis in germline mutation in ADCY5 movement disorder dyskinesia with orofacial involvement hereditary neurological disease dyskinesia with orofacial involvement, autosomal dominant https://www.malacards.org/card/dyskinesia_with_orofacial_involvement_autosomal_dominant FDFM SCTID:763352005 MESH:C564676 Orphanet:324588 ADCY5-related dyskinesia OMIM:606703 UMLS:C1847627 dyskinesia, familial, with facial myokymia MEDGEN:338280 A rare paroxysmal movement disorder, with childhood or adolescent onset, characterized by paroxysmal choreiform, dystonic, and myoclonic movements involving the limbs (mostly distal upper limbs), neck and/or face, which can progressively increase in both frequency and severity until they become nearly constant. Patients may also present with delayed motor milestones, perioral and periorbital dyskinesias, dysarthria, hypotonia, and weakness. MONDO:0800028 GARD:0012722