has material basis in germline mutation in ZMPSTE24 multiple congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome laminopathy restrictive dermopathy restrictive dermopathy 1 https://github.com/monarch-initiative/mondo/issues/4864 https://github.com/monarch-initiative/mondo/issues/7116 https://www.malacards.org/card/restrictive_dermopathy_1 tight skin contracture syndrome, lethal foetal hypokinesia sequence due to restrictive dermopathy restrictive dermopathy restrictive dermopathy 1, lethal MESH:C536920 MEDGEN:1812447 SCTID:400128006 DOID:0070369 GARD:0026425 MONDO:0800042 OMIM:275210 fetal hypokinesia sequence due to restrictive dermopathy hyperkeratosis-contracture syndrome UMLS:C5676878 A restrictive dermopathy that has material basis in homozygous or compound heterozygous mutation in the ZMPSTE24 gene on chromosome 1p34.