has modifier Autosomal dominant inheritance Autosomal recessive inheritance non-SCID combined immunodeficiency HELIOS deficiency https://github.com/monarch-initiative/mondo/issues/5261 MONDO:0800139 Orphanet:697389 A non-severe combined immunodeficiency caused by a loss-of-function variation in the IKZF2 gene that is characterized by recurrent upper respiratory infections, thrush and mucosal ulcers, and chronic lymphadenopathy. GARD:0026454