has material basis in germline mutation in NACC1 intellectual disability complex neurodevelopmental disorder Mendelian neurodevelopmental disorder NACC1-related neurodevelopmental disorder with epilepsy, cataracts and episodic irritability https://github.com/monarch-initiative/mondo/issues/6700 MONDO:0800475 GARD:0027073 A neurodevelopmental disorder caused by heterozygous variants in NACC1 and characterized by developmental delay, intellectual disability, epilepsy, cataracts, feeding difficulties, and recurring episodes of extreme irritability. Other phenotypes include hypotonia, delayed myelination, microcephaly, stereotypic hand movements, gastrointestinal tract issues, and sleeping problems. NACC1-related neurodevelopmental disorder with epilepsy, cataracts and episodic irritability