hypothyroidism myxedema coma https://github.com/monarch-initiative/mondo/issues/8513 UMLS:C0238298 Hypothyroid patients exhibit multiple physiologic alterations to compensate for the deficiency of thyroid hormone. Acute stressors like infection, myocardial infarction, cold exposure, and surgery in patients with poorly controlled hypothyroidism can overwhelm these homeostatic mechanisms and can lead to myxedema coma. It can also occur as a culmination of severe, longstanding hypothyroidism. PMID:34194879, https://www.ncbi.nlm.nih.gov/books/NBK545193/ MEDGEN:536791 MONDO:1010100 A rare complication of hypothyroidism characterized by altered mental status, hypothermia, and symptoms related to the slowing of other organ systems.