has material basis in germline mutation in hereditary neoplastic syndrome GPR161-related medulloblastoma predisposition https://github.com/monarch-initiative/mondo/issues/9877 MONDO:1010204 A predisposition to medulloblastoma, a tumor that originates in the cerebellum and dorsal brainstem, has a peak incidence in childhood, and makes up a large proportion of embryonal brain tumors due to a variation in the GPR161 gene. GPR161-related medulloblastoma predisposition