has material basis in germline mutation in predisposes towards SAMD9L ataxia-pancytopenia syndrome hereditary neoplastic syndrome familial monosomy 7 syndrome SAMD9L-related spectrum and myeloid neoplasm risk https://github.com/monarch-initiative/mondo/issues/8947 SAMD9L-related spectrum and myeloid neoplasm risk GARD:0028150 A susceptibility or predisposition to myeloid neoplasms in which the cause of the disease is a mutation in the SAMD9L gene. This condition is characterized by variable presentations of ataxia and cytopenia, myelodysplastic syndrome, monosomy 7 (acute myelogenous leukemia), and bone marrow failure. MONDO:1060111