inborn error of immunity growth hormone insensitivity syndrome with immune dysregulation STAT5 haploinsufficiency https://github.com/monarch-initiative/mondo/issues/9961 MONDO:1060224 GARD:0015006 STAT5A/5B haploinsufficiency STAT5 deficiency (haploinsufficient) A condition characterized by haploinsufficient levels of STAT5 protein due to reduced copy number or expression of the STAT5A and/or STAT5B genes, with consequent attenuation of STAT5-mediated cytokine signalling (including IL-7 and growth hormone pathways). This condition is also associated with altered lymphocyte homeostasis and modified susceptibility to lymphoma development.