brain disorder
Wernicke encephalopathy
Wernicke's encephalopathy
MONDO:0007020
DOID:2384
EFO:1001241
Wernicke's disease
SCTID:21007002
Orphanet:97354
dementia due to thiamine deficiency
An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. thiamine deficiency and chronic alcoholism are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to korsakoff syndrome. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3)
ICD9:265.1
ICD10CM:E51.2
UMLS:C0043121
MESH:D014899
alcohol-related disorders