develops from develops from capable of capable of mononuclear phagocyte professional antigen presenting cell macrophage Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid. histiocyte FMA:63261 BTO:0000801 A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. MESH:D008264 CALOHA:TS-0587 FMA:83585 monocyte myeloid leukocyte antigen processing and presentation of peptide or polysaccharide antigen via MHC class II phagocytosis pseudopodium organization