part of part of capable of capable of produces produces synovial cell stromal cell type B synovial cell 2010-09-13T03:39:14Z synovial fibroblast Type B synovial cells play a key role in the pathogenesis of chronic inflammatory diseases, such as rheumatoid arthritis, and are essential for the maintenance of normal joint functions. Fibroblast-like synoviocytes from different joints have different properties, which may contribute to the characteristic pattern of joint involvement in different types of arthritis. A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles. FMA:66788 BTO:0003652 fibroblast-like synoviocyte hyaluronan biosynthetic process synovial fluid synovial membrane of synovial joint