part of part of epithelial cell of large intestine transit amplifying cell of colon A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the colon. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells. colon transit amplifying cell transient amplifying cell of colon transient amplifying cell of crypt of Lieberkuhn of colon transit-amplifying cell of colon transit amplifying cell of large intestine transit amplifying cell of crypt of Lieberkuhn of colon transit amplifying cell of gut crypt of Lieberkuhn of colon