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    <!-- http://purl.obolibrary.org/obo/RO_0001025 -->

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    <!-- http://purl.obolibrary.org/obo/CL_0000623 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000623">
        <rdfs:label>natural killer cell</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CL_4047101 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_4047101">
        <rdfs:label>liver-resident natural killer cell</rdfs:label>
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        <dcterms:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2024-07-29T13:43:11Z</dcterms:date>
        <oboInOwl:hasExactSynonym>he-NK</oboInOwl:hasExactSynonym>
        <ns5:IAO_0000115>A natural killer cell resident to the liver, located in the hepatic sinusoids. In humans this cell type is distinguished from circulating natural killer cells by CD49a or CD69 gene expression. Liver-resident natural killer cells have also been shown to express CCR5, EOMES, KLRB1, GZMK, and CXCR6 in humans.</ns5:IAO_0000115>
        <dcterms:contributor>https://orcid.org/0000-0001-8134-3037</dcterms:contributor>
        <oboInOwl:hasExactSynonym>liver NK cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>intrahepatic NK</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>liver-specific natural killer cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>liver resident natural killer cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>lr-NK</oboInOwl:hasExactSynonym>
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        <rdfs:comment>Liver-resident natural killer cells play a crucial role in modulating the immune response during inflammation by balancing cytotoxic activity and cytokine production, thereby contributing to the maintenance of liver homeostasis and protection against excessive tissue damage.</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/UBERON_0001281 -->

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        <rdfs:label>hepatic sinusoid</rdfs:label>
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