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    <!-- http://purl.obolibrary.org/obo/GO_0004362 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0004362">
        <rdfs:label>glutathione-disulfide reductase (NADPH) activity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0015038"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0016209"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/GO_0016668"/>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/25461</ns3:IAO_0000233>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/25498</ns3:IAO_0000233>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/27180</ns3:IAO_0000233>
        <ns3:IAO_0000233 rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://github.com/geneontology/go-ontology/issues/30193</ns3:IAO_0000233>
        <oboInOwl:hasRelatedSynonym>glutathione S-reductase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>glutathione:NADP+ oxidoreductase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>glutathione-disulfide reductase (NADP) activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>NADPH-glutathione reductase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>GSH reductase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>GSSG reductase activity</oboInOwl:hasRelatedSynonym>
        <ns3:IAO_0000115>Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>glutathione reductase activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>EC:1.8.1.7</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>oxidized glutathione reduction</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>NADPH-GSSG reductase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasOBONamespace>molecular_function</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>Reactome:R-HSA-3323079</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>NADPH:oxidized-glutathione oxidoreductase activity</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>GO:0004362</oboInOwl:id>
        <oboInOwl:hasDbXref>MetaCyc:GLUTATHIONE-REDUCT-NADPH-RXN</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>glutathione-disulfide reductase activity</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>RHEA:11740</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Reactome:R-HSA-71682</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>glutathione-disulphide reductase activity</oboInOwl:hasExactSynonym>
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    <!-- http://purl.obolibrary.org/obo/GO_0015038 -->

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        <rdfs:label>glutathione disulfide oxidoreductase activity</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/GO_0016209 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GO_0016209">
        <rdfs:label>antioxidant activity</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/GO_0016668 -->

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        <rdfs:label>oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor</rdfs:label>
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