has participant hydron ATP(4-) ADP(3-) L-tyrosine residue O(4)-phosphonato-L-tyrosine(2-) residue protein kinase activity protein tyrosine kinase activity Reactome:R-HSA-2730843 Reactome:R-HSA-445091 Reactome:R-HSA-8849032 Reactome:R-HSA-428888 Reactome:R-HSA-9026890 Reactome:R-HSA-2671829 Reactome:R-HSA-2428926 Reactome:R-HSA-5654582 Reactome:R-HSA-5654587 Reactome:R-HSA-5654222 Reactome:R-HSA-8849042 Reactome:R-HSA-8848077 Reactome:R-HSA-1839098 Reactome:R-HSA-1295540 Reactome:R-HSA-2012087 Reactome:R-HSA-1250315 Reactome:R-HSA-873918 Reactome:R-HSA-9665411 Reactome:R-HSA-354124 Reactome:R-HSA-873919 Reactome:R-HSA-2730833 Reactome:R-HSA-2012082 Reactome:R-HSA-909718 Reactome:R-HSA-2730862 Reactome:R-HSA-9701488 MetaCyc:2.7.10.1-RXN Reactome:R-HSA-2730860 Reactome:R-HSA-1839067 Reactome:R-HSA-1839065 Reactome:R-HSA-9842648 Reactome:R-HSA-5218806 Reactome:R-HSA-8937807 Reactome:R-HSA-391871 Reactome:R-HSA-5218809 Reactome:R-HSA-445076 Reactome:R-HSA-9026510 Reactome:R-HSA-9606159 Reactome:R-HSA-909726 Reactome:R-HSA-9726848 Reactome:R-HSA-909729 Reactome:R-HSA-190388 Reactome:R-HSA-2730851 Reactome:R-HSA-9700168 Reactome:R-HSA-9033284 Reactome:R-HSA-8849068 Reactome:R-HSA-9700164 Reactome:R-HSA-190385 Reactome:R-HSA-4093332 Reactome:R-HSA-445085 Reactome:R-HSA-445084 Reactome:R-HSA-9672175 Reactome:R-HSA-9842651 Reactome:R-HSA-9672173 Reactome:R-HSA-5218812 Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. Reactome:R-HSA-909730 Reactome:R-HSA-9026502 Reactome:R-HSA-909732 Reactome:R-HSA-9703438 Reactome:R-HSA-9703437 Reactome:R-HSA-5655341 Reactome:R-HSA-9934751 Reactome:R-HSA-2730858 Reactome:R-HSA-3928627 Reactome:R-HSA-8857925 Reactome:R-HSA-5654545 Reactome:R-HSA-8853325 Reactome:R-HSA-5654428 Reactome:R-HSA-205289 Reactome:R-HSA-9674567 Reactome:R-HSA-8956659 Reactome:R-HSA-8875451 Reactome:R-HSA-1250348 Reactome:R-HSA-9026579 Reactome:R-HSA-1433488 Reactome:R-HSA-2671742 Reactome:R-HSA-170991 Reactome:R-HSA-508282 Reactome:R-HSA-2671850 Reactome:R-HSA-8853313 Reactome:R-HSA-9027425 Reactome:R-HSA-3928610 Reactome:R-HSA-9861469 Reactome:R-HSA-8964252 Reactome:R-HSA-9606163 Reactome:R-HSA-9606162 Reactome:R-HSA-190326 Reactome:R-HSA-9612996 Reactome:R-HSA-2029984 Reactome:R-HSA-3928604 Reactome:R-HSA-2029989 Reactome:R-HSA-9028728 Reactome:R-HSA-389354 Reactome:R-HSA-8853309 Reactome:R-HSA-451942 Reactome:R-HSA-380780 Reactome:R-HSA-2012073 Reactome:R-HSA-5654578 Reactome:R-HSA-9674558 Reactome:R-HSA-182969 protein-tyrosine kinase activity Reactome:R-HSA-1295609 Reactome:R-HSA-5655301 Reactome:R-HSA-5654575 Reactome:R-HSA-8875817 Reactome:R-HSA-5654628 Reactome:R-HSA-191062 Reactome:R-HSA-2201322 Reactome:R-HSA-9665705 Reactome:R-HSA-202248 Reactome:R-HSA-9665704 GO:0004718 Reactome:R-HSA-9665709 Reactome:R-HSA-202245 Reactome:R-HSA-9664976 Reactome:R-HSA-2454239 Reactome:R-HSA-170156 Reactome:R-HSA-5654634 Reactome:R-HSA-202233 Reactome:R-HSA-9709918 Reactome:R-HSA-5654631 Reactome:R-HSA-377640 Reactome:R-HSA-3928648 Reactome:R-HSA-2029268 Reactome:R-HSA-5654408 Reactome:R-HSA-5654407 Reactome:R-HSA-8848005 Reactome:R-HSA-8848124 Reactome:R-HSA-68954 Reactome:R-HSA-5218640 Reactome:R-HSA-6784319 Reactome:R-HSA-5218642 Reactome:R-HSA-8964242 Reactome:R-HSA-5654655 Reactome:R-HSA-8849463 Reactome:R-HSA-1839112 Reactome:R-HSA-1839110 Reactome:R-HSA-5654418 Reactome:R-HSA-1524186 Reactome:R-HSA-8849102 Reactome:R-HSA-1470009 Reactome:R-HSA-9026464 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Reactome:R-HSA-8851890 Reactome:R-HSA-5654607 Reactome:R-HSA-432129 Reactome:R-HSA-5690702 Reactome:R-HSA-5654605 Reactome:R-HSA-9700193 Reactome:R-HSA-2404199 Reactome:R-HSA-873922 Reactome:R-HSA-9712087 Reactome:R-HSA-9712085 Reactome:R-HSA-9712086 Reactome:R-HSA-9712082 Reactome:R-HSA-9931290 Reactome:R-HSA-873924 Reactome:R-HSA-2396594 Reactome:R-HSA-2029459 Reactome:R-HSA-3215391 Reactome:R-HSA-2404193 Reactome:R-HSA-389762 Reactome:R-HSA-2029453 Reactome:R-HSA-6790087 Reactome:R-HSA-5218851 Reactome:R-HSA-452097 Reactome:R-HSA-9037040 Reactome:R-HSA-2454208 Reactome:R-HSA-5607745 Reactome:R-HSA-112333 Reactome:R-HSA-9680248 Reactome:R-HSA-9706350 Reactome:R-HSA-9604767 Reactome:R-HSA-8848873 GO:0004713 Reactome:R-HSA-418163 Reactome:R-HSA-9032532 Reactome:R-HSA-9034714 Reactome:R-HSA-186786 Reactome:R-HSA-8848758 Reactome:R-HSA-9634390 Reactome:R-HSA-9732738 Reactome:R-HSA-8857555 Reactome:R-HSA-9018572 Reactome:R-HSA-1433506 Reactome:R-HSA-9624014 Reactome:R-HSA-9865196 Reactome:R-HSA-9027273 Reactome:R-HSA-399947 Reactome:R-HSA-9027272 Reactome:R-HSA-399946 Reactome:R-HSA-9860500 Reactome:R-HSA-9695834 Reactome:R-HSA-9021609 Reactome:R-HSA-69195 Reactome:R-HSA-1247844 Reactome:R-HSA-8855237 Reactome:R-HSA-8948143 Reactome:R-HSA-8942607 Reactome:R-HSA-9603420 Reactome:R-HSA-8848776 Reactome:R-HSA-2033488 Reactome:R-HSA-9034814 Reactome:R-HSA-2033486 Reactome:R-HSA-2033485 Reactome:R-HSA-183058 Reactome:R-HSA-912629 Reactome:R-HSA-201521 Reactome:R-HSA-399934 Reactome:R-HSA-1963586 Reactome:R-HSA-1963582 Reactome:R-HSA-983703 Reactome:R-HSA-372693 Reactome:R-HSA-1963581 Reactome:R-HSA-983709 Reactome:R-HSA-983707 Reactome:R-HSA-9860759 Reactome:R-HSA-8867041 Reactome:R-HSA-1225960 Reactome:R-HSA-177937 Reactome:R-HSA-177934 Reactome:R-HSA-9625487 Reactome:R-HSA-8847977 Reactome:R-HSA-9029155 Reactome:R-HSA-9029151 Reactome:R-HSA-2395412 Reactome:R-HSA-9613023 Reactome:R-HSA-8851933 Reactome:R-HSA-9670418 Reactome:R-HSA-9669890 Reactome:R-HSA-1225952 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