has primary output glucocorticoid glucocorticoid biosynthetic process glucocorticoid biosynthesis Reactome:R-HSA-194002 GO:0006704 glucocorticoid synthesis The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. glucocorticoid formation glucocorticoid anabolism glucocorticoid metabolic process biosynthetic process steroid hormone biosynthetic process