positively regulates positively regulates microtubule depolymerization positive regulation of microtubule polymerization or depolymerization regulation of microtubule depolymerization positive regulation of microtubule depolymerization upregulation of microtubule depolymerization Any process that activates or increases the frequency, rate or extent of microtubule depolymerization. positive regulation of microtubule catastrophe positive regulation of microtubule disassembly stimulation of microtubule depolymerization activation of microtubule depolymerization up regulation of microtubule depolymerization microtubule destabilization up-regulation of microtubule depolymerization GO:0031117 biological regulation positive regulation of protein depolymerization positive regulation of supramolecular fiber organization